biology biochemistry metabolism

Definition

Reverse Krebs Cycle

The Reverse Krebs Cycle (or Reductive Citric Acid Cycle) is a metabolic pathway used by certain bacteria and archaea to fix inorganic carbon dioxide () into organic compounds. Essentially running the Krebs cycle in reverse, it consumes energy in the form of ATP and reducing equivalents (like NADH or ) to synthesise acetyl-CoA from and water.