biology biochemistry metabolism
Definition
Reverse Krebs Cycle
The Reverse Krebs Cycle (or Reductive Citric Acid Cycle) is a metabolic pathway used by certain bacteria and archaea to fix inorganic carbon dioxide (
) into organic compounds. Essentially running the Krebs cycle in reverse, it consumes energy in the form of ATP and reducing equivalents (like NADH or ) to synthesise acetyl-CoA from and water.