Eletriptan

medicine

Definition

Eletriptan

Eletriptan is a second-generation triptan, a selective 5-HT1B/1D receptor agonist used for acute migraine treatment.

Network meta-analyses identify it as one of the most consistently effective triptans at the two-hour pain-free endpoint.

Pharmacokinetics

Bioavailability

Eletriptan exhibits higher oral bioavailability than sumatriptan, contributing to its robust efficacy profile.

Limitations

Contraindications

Contraindicated in cardiovascular disease, uncontrolled hypertension, and severe hepatic impairment due to vasoconstrictive properties.